Methods for Verifying GLP-1 Injectable Use

Methods for Verifying GLP-1 Injectable Use

Title
Brief Description
Other notes
Snap-on smart caps ( Mallya)
Replace the pen cap with a bluetooth-enabled cap that logs dose + timestamp. There used to be another one called GoCap that was acquired by BIgFoot Biomedical
Cap senses plunger travel and syncs data to an app/dashboard in real time. It looks like Mallya is now owned by Novo Nordisk. They also have smart insulin pens that track usage, but i don’t know of any that currently exist for GLP-1’s.
Smart-phone video DOT
Ask users to record a 10-sec selfie clip; Computer Vision / AI algorithm checks correct pen, site, angle & audible “click.”
vDOT is already CDC-endorsed for TB therapy and meets CMS telehealth rules. (cdc.gov)
Micro-slot live witness
60-second tele-nurse call or on-demand chat just at injection time.
Human attestation + screenshot → proof; no hardware mods required.
Smart drawer / fridge sensor
Existing ones like OmniCell’s MedTrack use a combination of RFID, weight pad under the pen, and a door-open sensor for medication management in more complicated settings. A stripped down version could be developed for at-home patient use with a single medication. (To be returned if they discontinue treatment)
There are many cheap, consumer-grade bluetooth or zigbee enabled sensors to detect doors being opened or closed. It wouldn’t be too hard to jury-rig one for a custom box setup. It couldn’t verify the injection, but at least could work outside cases of intentional patient misdirection.
Quarterly dried-blood-spot
Mail-in DBS card analysed for trough semaglutide; maintain discount if levels stay in therapeutic band.
LC-MS DBS assays for GLP-1 drugs already validated. (wada-ama.org)
NFC “fuse” tag on the disposable needle shield
Stick something like an NXP NTAG 213 TT / 424 TT chip on the needle sheath: it has the usual ISO-14443 NFC front-end plus a built-in “detection wire”. When that thin trace is intact, the chip reports Status = GOOD; once the trace breaks it irreversibly flips a one-time fuse bit so every later scan returns Status = OPEN.
Integration: 1. A die-cut label straddles the plastic needle shield and the pen barrel. 2. When the patient twists & removes the shield, the label tears the detection wire. 3. The pen’s own cap still snaps on normally—no effect on drug stability. User flow: 1. Tap phone to the pen before the jab → app sees GOOD. 2. Inject. 3. Tap again within (say) 2 minutes → app sees OPEN and submits a secure, time-stamped proof.